The Department of Medical Genetics Clinic together with the Department of Clinical Pathology offers an integrated process in diagnosing City Clinic patients and selecting the most proper therapeutic approach.
The hospital facility provides care to patients who require: genetic risk assessment, genetic tests, genetic diagnosis, genetic counseling and/or management of genetic diseases.
The laboratory offers the opportunity to:
- Isolate DNA from histological and cytological mixes. For patients with non-small cell lung cancer as an alternative method it is possible to implement the so-called liquid biopsy, or isolation and genotyping tumor markers (mutations in the EGFR gene) from venous blood.
- Personalize therapy for patients having:
̶ non-small cell lung cancer – EGFR / ALK mutations
̶ colorectal cancer – KRAS / NRAS / BRAF mutations
̶ melanoma – BRAF mutations.
The quality of the results is guaranteed both by the highly qualified team and the precision of the state-of-the-art equipment. Experts use tests in genome sequencing allowing them to find whether a patient’s tumor carries mutations that might be able to help in the treatment and match individual patients with existing therapies or clinical trials.
The Laboratory has got a Rotor-Gene Q, as well as a Cobas z480, two leading real-time PCR systems – thus guaranteeing precise and accurate results within a few days. The device allows precise diagnose of cancer findings in a patient’s body as well as providing the most proper therapy for each individual – the so called targeted therapy.